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Rapid and efficient inactivation of surface dried SARS-CoV-2 by UV-C irradiation

N. Ruetalo, R. Businger, M. Schindler, «Rapid and efficient inactivation of surface dried SARS-CoV-2 by UV-C irradiation», Biorxiv, Sept. 2020, pag. 10, doi: 10.1101/2020.09.22.308098.

Abstract

The SARS-CoV-2 pandemic urges for cheap, reliable and rapid technologies for disinfection and decontamination. We here evaluated the efficiency of UV-C irradiation to inactivate surface dried SARS-CoV-2. Drying for two hours did not have a major impact on the infectivity of SARS-CoV-2, indicating that exhaled virus in droplets or aerosols stays infectious on surfaces at least for a certain amount of time. Strikingly, short exposure of high titer surface dried virus (3*10^6 IU/ml) with UV-C light (0.66 mJ/cm2) resulted in a total reduction of SARS-CoV-2 infectivity. Together, our results demonstrate that SARS-CoV-2 is rapidly inactivated by relatively low doses of UV-C irradiation. Hence, UV-C treatment is an effective non-chemical possibility to decontaminate surfaces from high-titer infectious SARS-CoV-2.

Read the full article:
https://www.biorxiv.org/content/10.1101/2020.09.22.308098v1